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Silybin CAS#22888-70-6

Silybin CAS#22888-70-6

Basic Information

Silybin
Silibinin

Silybin, also called silibinin, is a major constituent of the silymarin complex and comprises silybin A and silybin B. It is used in laboratory studies of gene expression, cell proliferation, and enzyme behavior. Specific applications include RT-PCR investigations, PCNA and WST-1 assays, and research involving bacterial ATP synthase.

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product description

Primary Active Component of Silymarin:Represents 70–80% of the silymarin complex, ensuring high biological potency.


Strong Antioxidant and Anti:Inflammatory Activity – Effectively protects cells against oxidative stress and inflammation.


Broad Pharmacological Benefits:Exhibits anticancer, antidiabetic, antiviral, antimicrobial, and immunomodulatory properties.


Powerful Organ Protection:Provides significant hepatoprotective and neuroprotective effects.


Product Description of Silybin CAS#22888-70-6

Silybin, also referred to as silibinin, is the main biologically active component of the silymarin complex, accounting for approximately 70–80%, and consists of a mixture of silybin A and silybin B. Pharmacological studies have shown that silybin exhibits a wide range of biological activities, including strong antioxidant, anti-inflammatory, anticancer, antidiabetic, hepatoprotective, neuroprotective, antiviral, antimicrobial, and immunosuppressive effects.


Product Application of Silybin CAS#22888-70-6

Silibinin has been applied in various research studies, including:

Investigating its effects on the expression of genes related to chromatin regulation in prostate cancer using real-time polymerase chain reaction (RT-PCR).

Evaluating its influence on cell proliferation in platelet-derived growth factor (PDGF)–treated human Tenon’s fibroblasts (HTFs) by analyzing proliferating cell nuclear antigen (PCNA) expression and conducting water-soluble tetrazolium salt (WST-1) assays.

Examining its impact on the gene expression of stromelysin-1 (STM1), acetyl hexosamines, and collagen synthesis during the process of skin wound healing.

Studying its inhibitory activity against Escherichia coli ATP synthase.


Product Specifications

Parameters


Melting point164-174°C
alphaD20 +11° (c = 0.25 in acetone + alcohol)
Boiling point793.0±60.0 °C(Predicted)
density1.527±0.06 g/cm3(Predicted)
storage temp.-20°C
solubilityAcetone (Sparingly), DMSO, Methano (Sparingly)
formSolid
pkapKa 6.42±0.04 (Uncertain)
colorPale Yellow
Water Solubility54mg/L(24.99 ºC)
Merck138607
Stability:Stable. Incompatible with strong oxidizing agents, strong bases.
LogP4.232 (est)
CAS DataBase22888-70-6(CAS DataBase Reference)
Reference
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-37/39-24/25-22-36
RIDADR3172
WGK Germany3
RTECSDJ2981770
HS Code29329990
ToxicityLD50 intravenous in mouse: 1056mg/kg


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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.


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Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.


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