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Ginsenoside Rb1 CAS#41753-43-9

Ginsenoside Rb1 CAS#41753-43-9

Basic Information

Ginsenoside Rb1

Ginsenoside Rb1 is a glycosylated protopanaxadiol-type constituent of ginseng, including American ginseng. Sugar groups attached at two positions distinguish its molecular structure. It is used in natural-product research involving ginsenoside metabolism and cellular signaling, including investigations of ERK, AKT, and synapsin phosphorylation, rather than as evidence of a finished product's health effects.

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product description

Major Active Component of American Ginseng:Ginsenoside Rb1 is the principal bioactive constituent of American ginseng, ensuring high functional value.


Proven Anti-Aging Activity:Demonstrated anti-aging effects at both cellular and animal levels, supporting skin and overall vitality.


Enhances Hyaluronic Acid Synthesis:Its key metabolite 20GPPD increases HAS2 expression via ERK and AKT signaling, promoting hyaluronic acid production in human keratinocytes.


Advanced Cellular Signaling Activation:Activates ERK and AKT pathways in a dose-dependent manner, contributing to skin regeneration and anti-aging performance.


Product Description of Ginsenoside Rb1 CAS#41753-43-9

Ginsenoside Rb1 is a glycosylated protopanaxadiol (PPD)–type ginsenoside containing two sugar moieties attached at C-3 and two at C-20, and it represents the principal active component of American ginseng. Research has demonstrated that ginsenoside Rb1 exhibits anti-aging effects at both the cellular and animal levels.

Its main metabolite, 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD), has been shown in vitro to enhance HAS2 expression by activating ERK and AKT phosphorylation pathways in human keratinocytes in a dose-dependent manner.


Product Application of Ginsenoside Rb1 CAS#41753-43-9

Ginsenoside Rb1 is a major bioactive constituent of Panax ginseng that enhances neurotransmitter release by regulating synapsin phosphorylation through a cAMP-dependent protein kinase pathway. It has also been reported to exhibit immunostimulatory and anticancer activities.


Product Specifications

Parameters


Melting point197.5°C
Boiling point766.35°C (rough estimate)
density1.0971 (rough estimate)
refractive index1.6500 (estimate)
storage temp.2-8°C
solubilitymethanol: soluble9.80 - 10.20 mg/mL, clear, colorless to faintly yellow
pka12.85±0.70(Predicted)
formSolid
colorOff-White to Pale Beige
biological sourceplant root (Panax ginseng)
Stability:Hygroscopic
InChIKeyGZYPWOGIYAIIPV-VOKNSFSUNA-N
LogP2.900 (est)
CAS DataBase Reference41753-43-9(CAS DataBase Reference)


Safety Information


Hazard CodesXn,Xi,T,F
Risk Statements20/21/22-39/23/24/25-23/24/25-11
Safety Statements26-36-45-36/37-16-7
WGK Germany3
RTECSLZ5856000
HS Code29389090
Toxicityoms-rat-ipr 50 mg/kg CPBTAL 24,2400,76


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Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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