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Metronidazole CAS#443-48-1

Metronidazole CAS#443-48-1

Basic Information

Metronidazole

Metronidazole is a nitroimidazole antibiotic activated in susceptible microorganisms to inhibit bacterial DNA synthesis. It is used in pharmaceutical formulations for anaerobic bacterial infections, amoebiasis, and trichomoniasis, with applications extending across gastrointestinal, respiratory, urinary, skin, and other infection-related preparations. It is also used in pharmaceutical and microbiological research involving anaerobic organisms and protozoal activity.

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product description

Effective Anti-anaerobic Activity:Metronidazole has strong bactericidal effects against a wide range of anaerobic microorganisms.


Dual-action Mechanism:Both the drug and its metabolites inhibit bacterial DNA synthesis, effectively stopping bacterial growth and reproduction.


Clinically Proven Efficacy:Recognized by the World Health Organization as a key treatment for anaerobic infections with significant therapeutic results.


Broad Therapeutic Applications:Widely used for the prevention and treatment of various infections, including oral, respiratory, gastrointestinal, abdominal, skin, and systemic infections caused by anaerobic bacteria.

Product Description of Metronidazole CAS#443-48-1

Metronidazole is a nitroimidazole antibiotic active against anaerobic bacteria and Giardia, working by inhibiting bacterial DNA synthesis after metabolic activation. Designated by WHO in 1978 as the drug of choice for anaerobic infections, it was first used for vaginal trichomoniasis and is now widely applied to prevent and treat anaerobic infections throughout the body.


Product Application of Metronidazole CAS#443-48-1

This product has been used since 1959 for the treatment of vaginal trichomoniasis, and since 1970 for intestinal and extraintestinal amoebiasis. It is characterized by high efficacy, low toxicity, and a broad range of applications. However, animal studies have shown potential mutagenic and teratogenic effects.

Metronidazole exhibits strong antibacterial activity against most anaerobic bacteria. It is widely used in the treatment of amoebiasis, trichomoniasis, and various anaerobic infections.


Product Specifications

Parameters


Melting point159-161 °C (lit.)
Boiling point301.12°C (rough estimate)
density1.3994 (rough estimate)
refractive index1.5800 (estimate)
Fp9℃
storage temp.2-8°C
solubilityacetic acid: 0.1 M, clear, faintly yellow
formcrystalline
pkapKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain)
colorwhite to light yellow
Water Solubility<0.1 g/100 mL at 20 ºC
Merck146157
BRN611683
BCS Class1,3
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyVAOCPAMSLUNLGC-UHFFFAOYSA-N
LogP-0.02
IARC2B (Vol. 13, Sup 7) 1987
NIST Chemistry ReferenceMetronidazole(443-48-1)
EPA Substance Registry SystemMetronidazole (443-48-1)
Hazard CodesXn
Risk Statements40-46-45-39/23/24/25-23/24/25-11
Safety Statements36/37-45-53-16-7
WGK Germany3
RTECSNI5600000
F8
HS Code29332990
Hazardous Substances Data443-48-1(Hazardous Substances Data)


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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
We only provide highest quality goods available, accompanied by after support!

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FAQ

1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.


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Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.


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Please provide the product name, CAS number, required specifications, quantity, packaging requirements, and destination port. These details help us prepare an accurate quotation.


4. How do you control product quality?
We follow strict quality testing procedures supported by technical personnel, research equipment, and an established management system. Specific quality requirements can be confirmed before placing an order.


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Yes. Our technical team can assist with product selection based on your application and required specifications. Please share your intended use and key technical requirements.

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