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Loratadine CAS#79794-75-5

Loratadine CAS#79794-75-5

Basic Information

Loratadine

Loratadine is a second-generation tricyclic antihistamine that selectively blocks peripheral histamine H1 receptors. It is supplied for pharmaceutical formulation and used in preparations addressing allergic rhinitis and chronic urticaria, including nasal, ocular, and skin-related symptoms. Its long-acting profile and metabolism to desloratadine also make it a subject of pharmaceutical, pharmacological, and analytical research.

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product description

Fast-acting and Long-lasting Relief:Loratadine provides rapid onset of action with prolonged antihistamine effects, ensuring sustained symptom control.


Non-sedating and Hormone-free:As a second-generation antihistamine, it does not contain hormones and has no significant central nervous system inhibitory effects.


Effective Allergy Symptom Control:It relieves symptoms of allergic rhinitis, such as sneezing, runny nose, and nasal itching, as well as eye irritation and skin allergies like urticaria.


Safe and Well-tolerated:Lacks significant anticholinergic effects, and toxicological studies show no mutagenic or teratogenic risks in animals.


Product Description of Loratadine CAS#79794-75-5

Loratadine is a second-generation long-acting tricyclic antihistamine for anti-allergy use. It acts fast powerfully without hormones, and is metabolized into more potent desloratadine in vivo.

It competitively blocks histamine H1 receptors to ease allergic symptoms, with few anticholinergic and sedative effects. It relieves allergic rhinitis and chronic urticaria symptoms. Animal tests prove it has no mutagenic or teratogenic risks.


Product Application of Loratadine CAS#79794-75-5

Loratadine is a highly selective antihistamine for peripheral H1 receptors, providing strong and long-lasting effects. It is used in the treatment of allergic conditions such as allergic rhinitis.

As a nationally classified Class II antiallergic drug, it is applied to relieve both nasal and non-nasal symptoms associated with seasonal allergic rhinitis, as well as to alleviate symptoms of chronic urticaria.


Product Specifications

Parameters


Melting point134-136°C
Boiling point531.3±50.0 °C(Predicted)
density1.261±0.06 g/cm3(Predicted)
RTECSTM6129200
storage temp.2-8°C
solubilityDMSO: 26 mg/mL, soluble
formpowder
pka4.27±0.20(Predicted)
colorwhite
Water SolubilityIt is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck145578
BCS Class2
Stability:Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKeyJCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference79794-75-5(CAS DataBase Reference)
EPA Substance Registry System1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Hazard CodesXi
Risk Statements36/37/38
Safety Statements22-24/25-36-26
RIDADR3077
WGK Germany2
HS Code29333990
Hazardous Substances Data79794-75-5(Hazardous Substances Data)


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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
We only provide highest quality goods available, accompanied by after support!

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FAQ

1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.


2. Which industries do your products serve?
Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.


3. How can I get a quotation?
Please provide the product name, CAS number, required specifications, quantity, packaging requirements, and destination port. These details help us prepare an accurate quotation.


4. How do you control product quality?
We follow strict quality testing procedures supported by technical personnel, research equipment, and an established management system. Specific quality requirements can be confirmed before placing an order.


5. Can you help me select a suitable chemical?
Yes. Our technical team can assist with product selection based on your application and required specifications. Please share your intended use and key technical requirements.

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