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Progesterone CAS#57-83-0

Progesterone CAS#57-83-0

Basic Information

Progesterone
Crystals

Progesterone is a naturally occurring steroid hormone and an intermediate in steroid hormone synthesis. It occurs in two crystalline forms and is insoluble in water but dissolves in several organic solvents, including ethanol and acetone. These chemical characteristics are relevant to pharmaceutical processing and hormone-related formulations, without implying a specific therapeutic result.

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product description

Natural Endogenous Progestogen Hormone:Progesterone is the body’s primary naturally occurring progestogen, secreted by the ovarian luteal cells, ensuring excellent biological relevance and compatibility.


Key Steroid Hormone Intermediate:It serves as an important intermediate for the synthesis of all steroid hormones, making it highly valuable in pharmaceutical and hormone-related applications.


Dual Crystal Forms with Identical Activity:Available in both α-type and β-type crystal forms, both providing the same physiological activity for flexible formulation use.


Excellent Solvent Compatibility:Although insoluble in water, progesterone is readily soluble in ethanol, ether, chloroform, acetone, dioxane, and concentrated sulfuric acid, supporting diverse processing and formulation requirements.



Products Description of Progesterone CAS#57-83-0

Progesterone is an endogenous steroid hormone mainly secreted by ovaries, acting as a major natural progestogen and key intermediate for steroid hormone synthesis.

It has two crystal forms with identical bioactivity. Insoluble in water, it dissolves readily in most organic solvents and concentrated sulfuric acid.


Product Application of Progesterone CAS#57-83-0

Progesterone cooperates with estrogen to transform endometrium for embryo implantation, maintains pregnancy by restraining uterine contraction, and facilitates breast development for lactation. High doses suppress ovulation via hormonal feedback.

It is clinically applied to treat threatened abortion, irregular bleeding, dysmenorrhea, amenorrhea and other gynecological disorders, as well as prostatic hyperplasia and related complications.


Product Specifications

Parameters


Melting point128-132 °C (lit.)
alpha186 º (c=1, ethanol)
Boiling point394.13°C (rough estimate)
densityd23 1.166; d20 1.171
refractive index182 ° (C=2, Dioxane)
Fp2℃
storage temp.room temp
solubilityH2O: 25 mg/mL, may be clear to slightly hazy
formpowder
colorYellow to yellow-brown
biological sourcesynthetic (organic)
Water Solubility<0.1 g/100 mL at 19 ºC
Merck7773
BRN1915950
BCS Class4
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyRJKFOVLPORLFTN-LEKSSAKUSA-N
LogP3.87
CAS DataBase Reference57-83-0(CAS DataBase Reference)
NIST Chemistry ReferenceProgesterone(57-83-0)
EPA Substance Registry SystemProgesterone (57-83-0)


Safety Information


Hazard CodesXn,T,F
Risk Statements40-45-62-36-20/21/22-11
Safety Statements36/37-45-53-16
RIDADRUN 1648 3 / PGII
WGK Germany3
RTECSTW0175000
HS Code29372390
Hazardous Substances Data57-83-0(Hazardous Substances Data)
ToxicityLD50 intraperitoneal in rat: 327mg/kg









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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
We only provide highest quality goods available, accompanied by after support!

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FAQ

1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.


2. Which industries do your products serve?
Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.


3. How can I get a quotation?
Please provide the product name, CAS number, required specifications, quantity, packaging requirements, and destination port. These details help us prepare an accurate quotation.


4. How do you control product quality?
We follow strict quality testing procedures supported by technical personnel, research equipment, and an established management system. Specific quality requirements can be confirmed before placing an order.


5. Can you help me select a suitable chemical?
Yes. Our technical team can assist with product selection based on your application and required specifications. Please share your intended use and key technical requirements.

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