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5-Bromo-2-chloropyrimidine CAS#32779-36-5
Basic Information
5-Bromo-2-chloropyrimidine is a halogenated pyrimidine building block bearing bromine and chlorine at distinct ring positions. These substituents provide sites for further chemical transformation. It is used in pharmaceutical synthesis, including macitentan intermediates, and in cross-coupling studies involving indium-based organometallic reagents, supporting the construction of more complex substituted pyrimidine compounds.
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Valuable Pharmaceutical Intermediate: Widely used in the synthesis of macitentan, an endothelin receptor antagonist for pulmonary hypertension treatment.
Reactive Halogenated Structure: Contains both chloro and bromo substituents, enabling versatile chemical transformations and functionalization.
High Synthetic Utility: The pyrimidine core structure supports efficient incorporation into complex drug molecules.
Supports Advanced Drug Development: Facilitates the production of targeted therapeutic agents, making it important for modern pharmaceutical research.
Product Description of 5-Bromo-2-chloropyrimidine CAS#32779-36-5
5-Bromo-2-chloropyrimidine is a halogenated pyrimidine derivative featuring chloro and bromo substituents at the 2- and 5-positions of the ring. It is primarily used as a pharmaceutical intermediate in the synthesis of macitentan, an endothelin receptor antagonist employed in the treatment of pulmonary hypertension.
Product Applications of 5-Bromo-2-chloropyrimidine CAS#32779-36-5
5-Bromo-2-chloropyrimidine is used as a pharmaceutical intermediate in the synthesis of various drug compounds, including inhibitors. It is also utilized in cross-coupling reactions involving indium organometallic reagents with 2,5-dihalopyrimidines.
Parameters
Delivery Time
Inventory 2-3 working days New manufacturing 7-10 working days
Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
We only provide highest quality goods available, accompanied by after support!
1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.
2. Which industries do your products serve?
Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.
3. How can I get a quotation?
Please provide the product name, CAS number, required specifications, quantity, packaging requirements, and destination port. These details help us prepare an accurate quotation.
4. How do you control product quality?
We follow strict quality testing procedures supported by technical personnel, research equipment, and an established management system. Specific quality requirements can be confirmed before placing an order.
5. Can you help me select a suitable chemical?
Yes. Our technical team can assist with product selection based on your application and required specifications. Please share your intended use and key technical requirements.
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