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Ketoconazole CAS#65277-42-1
Basic Information
Ketoconazole is an imidazole-class pharmaceutical compound associated with fungal sterol biosynthesis and cytochrome enzyme interactions. In addition to pharmaceutical formulation applications, it is used in pharmacological research involving bioavailability and drug interactions. Its role as a cytochrome enzyme inhibitor makes it relevant to analytical investigations of compound metabolism rather than establishing any product-specific therapeutic performance.
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Broad-Spectrum Antifungal Activity：Ketoconazole is an imidazole antifungal effective against a wide range of fungal infections, including superficial and deep mycoses.
Selective Inhibition of Ergosterol Biosynthesis：It blocks ergosterol synthesis by interfering with fungal cytochrome P-450, disrupting cell membranes and preventing fungal growth.
Prevention of Fungal Growth and Spore Transformation：Ketoconazole inhibits fungal growth and prevents spores from forming mycelium, reducing reinfection risk.
Antibacterial and Clinical Versatility：It acts against Candida, Coccidioides, Histoplasma, Sporothrix, and Trichophyton, and is used to treat tinea pedis, tinea corporis, tinea cruris, thrush, and skin candidiasis.
Product Description of Ketoconazole CAS#65277-42-1
Ketoconazole is a broad-spectrum imidazole antifungal agent. It inhibits fungal cytochrome P450 to block ergosterol synthesis and damage fungal cell membranes. It suppresses fungal proliferation and spore development, exerting bacteriostatic and bactericidal effects. Effective against various fungi, it is widely used for treating multiple superficial and systemic fungal skin and mucosal infections.
Product Application of Ketoconazole CAS#65277-42-1
Ketoconazole is a broad-spectrum imidazole antifungal for various fungal infections including tinea pedis, candidiasis and systemic mycoses. As a CYP3A4 inhibitor, it is also widely used in pharmacological research for bioavailability assessment, antitumor study and drug interaction analysis.
Parameters
Safety Information
Delivery Time
Inventory 2-3 working days New manufacturing 7-10 working days
Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.
2. Which industries do your products serve?
Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.
3. How can I get a quotation?
Please provide the product name, CAS number, required specifications, quantity, packaging requirements, and destination port. These details help us prepare an accurate quotation.
4. How do you control product quality?
We follow strict quality testing procedures supported by technical personnel, research equipment, and an established management system. Specific quality requirements can be confirmed before placing an order.
5. Can you help me select a suitable chemical?
Yes. Our technical team can assist with product selection based on your application and required specifications. Please share your intended use and key technical requirements.
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White crystalline powder; Colorless crystals
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Caustic Soda
NaOH
Flakes; Granules; Beads; Lumps
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Crystals; Granules; Powder
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White fine powder
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Colorless liquid
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Colorless liquid
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SLES
Colorless to pale yellow viscous liquid
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MAA
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