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Fluconazole CAS#86386-73-4

Fluconazole CAS#86386-73-4

Basic Information

Fluconazole

Fluconazole is a triazole-class pharmaceutical compound described through its relationship with fungal cytochrome-dependent enzymes and sterol biosynthesis. The supplied application context is systemic pharmaceutical formulations. Its triazole identity and enzyme-related biochemical profile distinguish it from imidazole compounds, although the available material does not define a physical appearance, hydration state or solvent compatibility for this particular product.

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product description

Broad-Spectrum Antifungal Activity:Fluconazole provides effective inhibition against a wide range of fungal pathogens, making it suitable for multiple antifungal applications.


Systemic Antifungal Efficacy:As a systemic antifungal agent, it delivers reliable therapeutic performance throughout the body for deep and systemic fungal infections.


Highly Selective Mechanism of Action:It selectively inhibits fungal cytochrome P-450-dependent enzymes, ensuring targeted antifungal activity with high specificity.


Potent Inhibition of Fungal Sterol Synthesis:Fluconazole strongly and specifically blocks fungal sterol biosynthesis, disrupting fungal cell membrane formation and preventing growth.


Product Description of Fluconazole CAS#86386-73-4

Fluconazole is an advanced triazole antifungal medication initially developed by Pfizer Pharmaceuticals in the United States. It offers broad-spectrum antifungal activity and is designed for systemic use. Fluconazole selectively targets and inhibits fungal cytochrome P-450-dependent enzymes, and it is also a powerful and specific inhibitor of fungal alcohol synthesis.

Product Application of Fluconazole CAS#86386-73-4

Fluconazole is a broad-spectrum triazole antifungal drug with an antibacterial spectrum similar to ketoconazole. It is long-acting, highly effective against deep fungal infections, and provides strong antifungal activity with good oral absorption. It is mainly used for the treatment of candidiasis and cryptococcosis, and is also effective for oropharyngeal candidiasis in cancer patients.

Product Specifications

Parameters


Melting point138-140°C
Boiling point579.8±60.0 °C(Predicted)
density1.05
Fp9℃
storage temp.2-8°C
solubilityDMSO: 5 mg/mL
formsolid
pkapKa 1.76±0.1(H2O t=24 I=0.1(NaCl)) (Uncertain)
colorWhite to Off-White
Water Solubility1g/L(temperature not stated)
Merck144122
BCS Class1,3
InChIInChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
InChIKeyRFHAOTPXVQNOHP-UHFFFAOYSA-N
SMILESC1(C=CC(F)=CC=1F)C(O)(CN1N=CN=C1)CN1N=CN=C1
CAS DataBase Reference86386-73-4(CAS DataBase Reference)


Safety Information


Hazard CodesXn,Xi,T,F
Risk Statements22-36/37/38-20/21/22-39/23/24/25-23/24/25-11
Safety Statements26-36-36/37/39-24/25-45-36/37-16-7
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany3
RTECSXZ4810000
HS Code29336990
Hazardous Substances Data86386-73-4(Hazardous Substances Data)


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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
We only provide highest quality goods available, accompanied by after support!

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FAQ

1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.


2. Which industries do your products serve?
Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.


3. How can I get a quotation?
Please provide the product name, CAS number, required specifications, quantity, packaging requirements, and destination port. These details help us prepare an accurate quotation.


4. How do you control product quality?
We follow strict quality testing procedures supported by technical personnel, research equipment, and an established management system. Specific quality requirements can be confirmed before placing an order.


5. Can you help me select a suitable chemical?
Yes. Our technical team can assist with product selection based on your application and required specifications. Please share your intended use and key technical requirements.

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