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Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid CAS#1493-13-6

Basic Information

Trifluoromethanesulfonic acid
CF₃SO₃H

Trifluoromethanesulfonic acid, or triflic acid, is a non-oxidizing superacid with high thermal stability and strong resistance to oxidation and reduction. The anhydrous form is especially valuable where intense, nonaqueous acidity is required. It catalyzes Friedel–Crafts acylation, alkylation and polymerization, and serves as a nonaqueous acid titrant or ESR solvent. It is also used in pharmaceutical, agrochemical, polymer, nucleoside, peptide, steroid and glycoside synthesis.

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product description

Extremely Strong Acid:Triflic acid is recognized as one of the strongest acids, belonging to the superacid class.


High Thermal and Chemical Stability:It is non-oxidizing, thermally stable, and resistant to both oxidation and reduction.


Versatile in Fine Chemical and Pharmaceutical Synthesis:Used in the production of pharmaceuticals, agricultural chemicals, polymers, nucleosides, antibiotics, steroids, proteins, and glycosides.


Effective Anhydrous Form: The anhydrous form is widely utilized in fine chemical synthesis due to its reactivity and utility.

Product Description of Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid (triflic acid, TfOH) has the formula CF3SO3H and is classified as a superacid, ranking among the strongest acids known.

It features non-oxidizing property, high thermal stability, and resistance to oxidation and reduction. Widely applied in pharmaceuticals, agrochemicals and polymer synthesis, its anhydrous form is especially valuable for fine chemical production.

In pharma manufacturing, it is used to synthesize nucleosides, antibiotics, steroids, proteins and glycosides. Triflic anhydride is highly reactive with water and has significant toxicity.


Product Application of Trifluoromethanesulfonic acid CAS#1493-13-6

Trifluoromethanesulfonic acid acts as a catalyst for Friedel-Crafts acylation, alkylation and polymerization reactions. It also serves as a solvent for ESR analysis and a strong non-aqueous acid titrant. Combined with trifluoroacetic acid, it is used in solid-phase peptide synthesis. It is acknowledged as one of the strongest monoprotic acids.

Product Specifications

Parameters


Melting point-40 °C
Boiling point162 °C (lit.)
density1.696 g/mL at 25 °C (lit.)
vapor density5.2 (vs air)
vapor pressure8 mm Hg ( 25 °C)
refractive indexn20/D 1.327(lit.)
RTECSPB2771000
FpNone
storage temp.Store below +30°C.
solubilityMiscible in H2O
pka-14(at 25℃)
formFuming Liquid
colorslightly brown
Specific Gravity1.696
PH<1 (H2O)
Water SolubilitySOLUBLE
SensitiveHygroscopic
Merck149,676
BRN1812100
Stability:Stable. Incompatible with acids, alkalis, metals.
InChIKeyITMCEJHCFYSIIV-UHFFFAOYSA-N
LogP0.3 at 25℃
CAS DataBase Reference1493-13-6(CAS DataBase Reference)
NIST Chemistry ReferenceCF3SO3H(1493-13-6)
EPA Substance Registry SystemMethanesulfonic acid, trifluoro- (1493-13-6)
Hazard CodesC
Risk Statements21/22-35-10
Safety Statements26-36/37/39-45
RIDADRUN 3265 8/PG 2
WGK Germany2
F3-10
Hazard NoteCorrosive/Hygroscopic
TSCAYes
HazardClass8
PackingGroupII
HS Code29049020
ToxicityLD50 orally in Rabbit: 1605 mg/kg LD50 dermal Rat > 2000 mg/kg


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Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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1. What products does Shandong Junzheng Chemical supply?
We supply inorganic chemicals, organic solvents, water treatment chemicals, and surfactants, including calcium chloride, soda ash, sodium bicarbonate, caustic soda, citric acid, ethyl acetate, and SLES. Please contact us to confirm specific product availability.


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Our products serve pharmaceutical, agrochemical, dye, rubber, construction, coal processing, and other chemical industries. Product suitability depends on the required grade, specifications, and application.


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